PreSonus AudioBox USB 96 vs Focusrite Scarlett 2i2 (4th Gen)

PreSonus AudioBox USB 96 vs Focusrite Scarlett 2i2 (4th Gen) compared — specs, features, and which one to buy for your setup. See the full breakdown on CreatorConfig.

PreSonus AudioBox USB 96
PreSonus
PreSonus AudioBox USB 96
$199
Focusrite Scarlett 2i2 (4th Gen)
Focusrite
Focusrite Scarlett 2i2 (4th Gen)
$199.99

The Ruling

PreSonus AudioBox USB 96 or Focusrite Scarlett 2i2 (4th Gen)? Get the Focusrite Scarlett 2i2 (4th Gen).

The Focusrite Scarlett 2i2 (4th Gen) wins Preamps and Creator Features. It is the pricier of the two at $199.99, so the PreSonus AudioBox USB 96 stays the pick if $0.99 matters more than those specs.

Check price on Amazon

At a Glance

Where each one actually leads

Every axis is scored out of 10 from the catalog specs below. The scores are relative to the products on this page, so a 10 means “best of these”, not “perfect”, and two identical columns mean the catalog genuinely cannot separate them. Axes the catalog holds no figure for on both sides are left off entirely rather than guessed at.

CategoryPreSonus AudioBox USB 96Focusrite Scarlett 2i2 (4th Gen)
Audio Resolution10/1010/10
Preamps6.9/1010/10
Mic Inputs10/1010/10
Monitoring10/1010/10
Creator Features5/1010/10
Connectivity10/1010/10

The Split

What each one wins

PreSonus AudioBox USB 96

Desktop audio interface intended for creator workflows, microphone input, monitoring, and clean signal routing.

It gives up loopback and preamp gain to the Focusrite Scarlett 2i2 (4th Gen). The two are priced the same, so price does not decide it.

Leads on

  • Nothing on the spec sheet goes this one’s way.

Focusrite Scarlett 2i2 (4th Gen)

Two-channel USB-C audio interface with studio-grade preamps for recording, streaming, and vocals.

On paper the Focusrite Scarlett 2i2 (4th Gen) takes loopback (Yes), preamp gain (69dB, +34dB) and dynamic range (120dB, +15dB). It concedes nothing measurable on the sheet. The two are priced the same, so price does not decide it.

Leads on

  • Loopback
    Yes
    No

    Loopback routes computer audio back into the stream without a second interface or cable.

  • Preamp Gain +34dB
    69dB
    35dB

    More gain drives quiet dynamic microphones like the SM7B without a separate booster.

  • Dynamic Range +15dB
    120dB
    105dB

    Wider converter dynamic range means less noise between the quietest and loudest parts of a take.

Where they’re identical

These 9 specs are the same on both of them, so none of it is part of the decision.

  • Sample Rate 192kHz
  • Bit Depth 24-bit
  • Phantom Power Yes
  • XLR Inputs 2
  • Headphone Outputs 1
  • Direct Monitoring Yes
  • ADAT Expansion No
  • Bus Powered Yes
  • TRS Outputs 2

The Record

19 specs, grouped by area

Full specification comparison of PreSonus AudioBox USB 96 and Focusrite Scarlett 2i2 (4th Gen), grouped by area.
Specification
PreSonus
PreSonus AudioBox USB 96
Focusrite
Focusrite Scarlett 2i2 (4th Gen)
Audio ResolutionEven
Sample Rate192kHz192kHz
Max Sample Rateno data192kHz
Bit Depth24-bit24-bit
PreampsFocusrite Scarlett 2i2 (4th Gen)
Preamp Gain35dB✓ 69dB
Dynamic Range105dB✓ 120dB
Mic InputsEven
XLR Inputs22
MonitoringEven
Headphone Outputs11
Direct MonitoringYesYes
Creator FeaturesFocusrite Scarlett 2i2 (4th Gen)
LoopbackNo✓ Yes
ADAT ExpansionNoNo
MIDI I/OIn/OutNone
Bundled Softwareno dataHitmaker Expansion, Ableton Live Lite, Pro Tools Intro+, Cubase LE
ConnectivityEven
TRS Outputs22
Connection Typeusb-a, xlr, trsusb-c, xlr, trs
PowerEven
Bus PoweredYesYes
Phantom PowerYesYes
BuildNot enough data
Dimensionsno data180 x 117 x 47.5 mm
Weight0.59 kg0.595 kg
CompatibilityNot enough data
Operating Systemwindows, macosno data

A group is won by whoever takes more of its rows outright. Specs the catalog cannot rank are shown but never decide a group.

Bottom Line

Who each one is for

The Focusrite Scarlett 2i2 (4th Gen) is the pick on the specs the catalog holds, but “better on paper” and “right for you” are different questions. Each case below names what the product is actually good at and who that suits.

The alternative
Budget Pick

At $199.00, the PreSonus AudioBox USB 96 is the most affordable option in this comparison. It trades raw specs for a simpler, more focused experience. Covers the essentials without stretching your budget.

  • + Exclusive connectivity: USB-A
  • × Weaker dynamic range (105dB vs 120dB)
  • × Weaker preamp gain (35dB vs 69dB)
  • × Weaker loopback (No vs Yes)

Also worth knowing

  • ✓ Budget is your top priority — $0.99 less than the priciest option
  • ✓ You have MIDI gear to plug in without a separate adapter

Look elsewhere if

  • × You need the best dynamic range available
  • × You need the best preamp gain available

Best for budget-conscious creators.

Our pick
Best ValuePremium Pick

The Focusrite Scarlett 2i2 (4th Gen) is the priciest at $199.99, but leads on specs where it counts. It leads in dynamic range (120dB) and preamp gain (69dB). Offers the most spec advantages per dollar in this comparison.

  • + Better dynamic range (120dB vs 105dB)
  • + Better preamp gain (69dB vs 35dB)
  • + Better loopback (Yes vs No)
  • + Exclusive connectivity: USB-C

Also worth knowing

  • ✓ You want the stronger dynamic range (120dB)
  • ✓ You want the stronger preamp gain (69dB)
  • ✓ You want USB-C for a modern, reversible connector
  • ✓ You want to capture computer audio without a second interface

Best for value-focused buyers, professionals who want the best.

Frequently Asked Questions

What is the main difference between PreSonus AudioBox USB 96 and Focusrite Scarlett 2i2 (4th Gen)?

The clearest difference is loopback, which the Focusrite Scarlett 2i2 (4th Gen) has and the PreSonus AudioBox USB 96 does not. Across the catalog's specification sheet the two differ on 3 specs. They match on 9 specs, including sample rate, bit depth and phantom power. Two audio interfaces from PreSonus and Focusrite, each taking a different approach to audio quality and I/O flexibility.

Which is better for streaming, PreSonus AudioBox USB 96 or Focusrite Scarlett 2i2 (4th Gen)?

Get the Focusrite Scarlett 2i2 (4th Gen). The Focusrite Scarlett 2i2 (4th Gen) wins Preamps and Creator Features. It is the pricier of the two at $199.99, so the PreSonus AudioBox USB 96 stays the pick if $0.99 matters more than those specs.

What do the PreSonus AudioBox USB 96 and Focusrite Scarlett 2i2 (4th Gen) have in common?

Both share 9 specifications in the catalog, including sample rate (192kHz), bit depth (24-bit), phantom power (Yes) and XLR inputs (2), among others. None of those is a reason to pick one over the other.

Related Comparisons

PreSonus AudioBox USB 96 vs Audio-Technica AT-UMX3 Desktop Mixer Compare → Focusrite Scarlett 2i2 (4th Gen) vs Focusrite Scarlett 4i4 4th Gen Compare → PreSonus AudioBox USB 96 vs EVO 4x4 USB-C Audio Interface Compare → Focusrite Scarlett 2i2 (4th Gen) vs Audio-Technica AT-UMX3 Desktop Mixer Compare → PreSonus AudioBox USB 96 vs M-Audio M-Track 2x2M-C Compare → Focusrite Scarlett 2i2 (4th Gen) vs EVO 4x4 USB-C Audio Interface Compare →